Research

Surpass the diffraction limit to achieve super resolution and separate molecules by their timing footprint.

Enabling cutting edge research and innovation​

In research, advanced imaging technologies offer transformative capabilities. We are offering those technologies with our SPAD arrays and cameras. For example:

  • SPAD arrays are used in confocal microscopes, enabling optical super resolution down to 100 nm.
  • Time-gated imaging with SPAD cameras is used in widefield fluorescence lifetime imaging microscopy (FLIM), enabling molecule identification by their timing footprint. 
  • Light-in-flight imaging (based on time-gated capabilities of SPAD cameras) enables scientists to capture and analyze the propagation of light through various media.
  • Time-correlated signal photon counting offers to analyze complicated photophysics of molecules.

Benefits of SPAD technology
for this application

High-resolution SPADs

We are offering SPAD arrays with 23 to 512x512 pixels.

Single-photon sensitivity

Due to high sensitivity, our detectors offer unprecedented data quality and image sharpness.

Extremely high speed

We offer frame rates up to 100’000, 550’000 and 2’000’000 fps our image sensors, line sensors, and point sensors, respectively.

Time-gated imaging

SPADs support precise gating, allowing for accurate time-resolved imaging. ​

Time-tagged detection

Time-correlated signal photon counting offers to analyze complicated photophysics of molecules.

Examples / Application results

SPAD512S LIF2

Light-in-flight imaging

SPADs capture rapid light propagation with exceptional timing precision, enabling detailed analysis of fast-moving light phenomena.

F1-Large, SPAD camera

Multiplexed lifetime imaging

Optimized acquisition scheme achieves single-molecule lifetime measurements with high precision.

SPAD Super resolution microscopy - Credits PicoQuant

Super resolution microscopy

Eliminate the confocal trade-off between the spatial resolution and signal-to-noise ratio

Pi Imaging support team

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